本文与 Jesus de Pedro Cuesta 及其同事在《神经病学、神经外科学与精神病学杂志》上发表的论文有关，该文提示散发型克-雅二氏病（CJD）病例中某些类型手术的发生率有所升高，尤其是 10 年以上的手术。因此本文意义十分重大，其含义在于：部分看似散发型的 CJD 病例实际上可能由既往手术时的感染引起。
This article relates to a paper published by Jesus de Pedro Cuesta and colleagues in the Journal of Neurology, Neurosurgery and Psychiatry, which suggest that there is an increased frequency of some types of surgery in cases of sporadic CJD, particularly surgery more than 10 years in the past. This is therefore an article of significant interest as the implication is that some cases of apparently sporadic CJD may actually be caused by infection at the time of past surgery.